Not sure what kind of crowd we'll get at that one - maybe it'd be better for her to experience Villa Park for the first time at full volume?
On a similar note to my above point, I think the atmosphere is what really makes a live game, particularly for many who haven't been before. If you don't think she'll mind hearing many more 'colourful' comments, then I'd say go for the Upper Holte, without question. If standing regularly is an issue, go for something right at the front of the upper tier if you can get it, or towards the wings.