6 out would be painful but I suspect a fair few people are going to be in the same position.
Livramento is well owned, Ronaldo, DDG and Dalot have shot up in ownership, Cancelo is on a red. People will still have Spurs players to ditch. Brighton defence was popular. People were starting to get Villa players again.
I suspect a lot of people will be low scoring this week. I've only got 9 players available myself and I have doubts on some of these.
The questions then becomes how good could your FH team be, how much could you shoot ahead of everyone else struggling, would you still have selection issues next week and is there going to be a even more decimated (or even big DGW) week in the future?
Personally, I'd roll the dice this week and save it for down the line. We've just had the most covid positives the Premier League have ever seen and I suspect it'll roll into next week too. We're also going to have a lot of delayed fixtures starting to pile up (potentially whilst players are at the Africa Cup).