This weekend is a good time to rest a few, i'd be tempted to rest James Collins ( can be a bit injury prone ), Petrov, Gabby, One of the Wingers and possibly Milner.
Wouldn't change the entire team as we still want to win the game but its definately a game to use the squad and give Delph, Delfuneoso, Reo Coker, Young etc some playing time.