Are you going to be driving? If not, you will probably be better on International Drive as it's easier for catching the bus and walking to places to eat. We are stopping in the Lake Buena Vista area as we have a car and it's a bit nicer.
Are you and your family just wanting to do Disney? If so then a week is fine - but what about Universal Studios, Sea World, Kennedy Space Centre, all the different water parks, big shopping malls, shooting ranges etc.