Are you counting the games in pre-season and for reserves? and many many years in one of the most competitive academies in the world.
And yes i do think there would be a noticeable improvement, positioning knowledge is specific to particular positions. Look at Jedinak being a prime example of that or centre-backs when played at DM.
Also, don't underestimate the difficulty in playing out-of-position in a massively under-performing defence that is lacking organisation.
Just out of interest, who do you think should be the CB pairing?